PostDoc heart failure (f/m/d)
Universit盲tsmedizin 骋枚迟迟颈苍驳别苍 (UMG)

骋枚迟迟颈苍驳别苍

Temporary

Full Time

Published: 2025-03-26

The Institut f眉r Herz- und Kreislaufphysiologie of the University Medical Centre 骋枚迟迟颈苍驳别苍 is looking for a new position to 01.05.2025

PostDoc (f/m/d)

full time, 38,5 hours per week, limited for 2 years and further extension is anticipated

Heart failure is one of the most common causes of morbidity and mortality worldwide. At the cell level, the injured heart reacts with complex and stereotypical remodeling processes in cardiomyocytes and in the so-called non-cardiomyocytes (fibroblasts, endothelial cells, immune cells, etc.). Striking changes in these cells are redox-dependent modifications to regulatory proteins. An imbalance in the production of reactive oxygen species and an altered "redox state" is involved in many cardiac stress reactions that are involved in the development of heart failure. As part of our projects, we develop technical tools for the quantification of redox changes in cardiomyocytes and non-cardiomyocytes and their consequences for the function at cell and organ level (see for example ).

Your tasks

driving experimental projects that study redox modifications in genetically modified induced pluripotent derived cardiomyocytes
apply genetically encoded biosensor
apply redox proteomics methods and analyze proteomics data sets
analyze the consequences of redox modifications for cardiomyocyte physiology (force of contraction etc.)
collaborative work in our research team, for example together with PhD or BSc/MSc students
teaching of undergraduate students in physiology as part of the study programmes human medicine, dental medicine, molecular medicine and cardiovascular physiology

Your qualifications

enthusiasm for science and interest in understanding redox biology
BSc/MSc degree and PhD in molecular or cell biology, biochemistry or a related subject
experience with analyzing protein modifications and analyzing proteome data sets
experience with analyzing cardiomyocyte physiology
ability to work independently and also in a team
good command of the English language and basic knowledge in German language

We look forward to receiving your application!

The University Medical Center 骋枚迟迟颈苍驳别苍 (UMG) unites the Medical Faculty of the Georg-August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high-quality patient care, excellent research, modern teaching and innovative transfer.

骋枚迟迟颈苍驳别苍 as a city of science is located in the center of Germany and the University Medical Center 骋枚迟迟颈苍驳别苍 is integrated into an attractive network of university and non-university scientific institutions.

Our goal as University Medical Center 骋枚迟迟颈苍驳别苍 is professional equality for all genders. We strive to equalize the gender ratio in areas where there is underrepresentation. The University Medical Center 骋枚迟迟颈苍驳别苍 is particularly committed to the professional participation of severely disabled people and therefore welcomes applications from severely disabled people. In the case of equal suitability, applications from severely disabled persons will be given preferential consideration in accordance with the relevant regulations. We kindly ask you to indicate a disability/equal status in your letter of application in order to safeguard your interests.

Universit盲tsmedizin 骋枚迟迟颈苍驳别苍
Institut f眉r Herz- und Kreislaufphysiologie
Prof. Dr. D枚rthe Katschinski
Direktorin
Robert-Koch-Stra脽e 40
37073 骋枚迟迟颈苍驳别苍